Ketoconazole: Antifungal Medication for Dogs - VetRxDirect
Most fungal infections of the skin are caused by a type of yeast called Malassezia. This yeast usually lives in small amounts on a dog’s skin or in the ears. Allergies, moisture trapped in the fur, harsh flea and tick chemicals, sensitivity to cleaning products, and many other factors can lead to an overgrowth of this organism. Treatment of mild infections may include regular medicated shampoos, medicated cleansing pads, and/or topical antifungal cream. More severe infections may require oral anti-fungal medications for weeks to months. Of course, long term treatment is most successful when the inciting cause is found and eliminated.
The different types of over the counter ringworm treatment for dogs vary, so it is best to speak with a veterinarian first before selecting atreatment option. Topical ringworm treatments for dogs include Cruex cream, Desenex cream, Lotrimin cream, lotion, and solution), miconazole (Monistat-Derm cream), ketoconazole (Nizoral cream), and terbinafine ( cream and solution). Medicated shampoos such as Selsun Blue or anti-fungal shampoos that contain ketoconazole 2% (Nizoral) or the newerciclopriox are effective in treating mild cases of ringworm.
Ketoconazole is an antifungal medicine used predominantly for treating fungal infections, though it has additional properties which can help in the treatment of truncal alopecia. In the past it was used for Cushing’s disease but this is no longer common as the medicine can place extra stress on the liver, even leading to liver failure in rare cases. It is derived from the organic compound imidazole and works by inhibiting the process vital for the growth of fungus. In large doses it can puncture holes in the cell membrane of fungal structures destroying them by causing essential components to leak out.
If you notice your dog becoming patchy and shedding large amounts of hair you should speak to the vet for diagnosis as they could have mange or lupus.
Fungistatic Vs Fungicide: Know The Difference
Derivatives of imidazole including ketoconazole are usually fungistatic. This means that instead of directly killing fungi, they limit its growth and rely on natural processes to eliminate the infection from the body. When used in higher doses, they can become fungicidal and attack cell membranes. Fungistatic drugs are more often used as they tend to be safer, but they may not be a good option for treating life threatening infections or when the dog’s immune system function is reduced. If you’re interested in further comparing the differences you can check out the page on .
miconazole lotion is an antifungal medication used on dogs and cats which prevents fungus from growing on the skin. miconazole lotion is used to treat fungal skin infections such as ringworm and yeast infections. Miconazole lotion may also be used for purposes other than those listed.
Ketoconazole is commonly prescribed by vets, even though it has not yet been approved by the FDA for veterinary purposes. Some ‘azole’ antifungal medicines have been approved for veterinary use by the FDA, however, including thiabendazole. When treating certain conditions like aspergillosis, thiabendazole is thought to be just as effective. You can .
Even though ketoconazole isn’t FDA-approved, many veterinary professionals consider it to be safe for use. Safety regarding the external use of ketoconazole creams and shampoos has not yet been established, however there are typically less side effects reported following topical use aside from skin irritation in rare cases.
Contraindications & Drug Interactions
There aren’t many contraindications associated with this medicine, though it could be unsuitable for dogs with liver problems, especially when given at higher doses. Drug interactions are relatively extensive.
Monistat is an anti-fungal topical medication that’s used for treating yeast infections. Your pet dog’s skin and ears are most vulnerable to such a Candida outbreak. This popular product can effectively eliminate fungi for Fido.